Risky business 英文参考文献.docVIP

Petsko Genome Biology 2011,12:119 /2011/12/6/119 COMMENT Risky business Gregory A Petsko* My parents came of age during the Great Depression of ey won’t admit it, of course (rhabdophobia - fear of the 1930s - you know, the economic catastrophe that being criticized), but they have become so conservative was caused by the ?nancial industry. (Oh yes, now that you mention it, the ?nancial industry caused the latest one too. And most of the ones in between. Good thing about how they give their money away, you’d swear they had harpaxophobia (fear of having one’s valuables stolen). We’ve all encountered this, I suspect - I know I have. we ?nally reformed the rules regulating that industry It’s gotten to the point where, in order to get a research and put the worst crooks behind bars - what do you mean, we didn’t?) proposal funded, you need to have already done nearly all the experiments you propose to do, so as to assure the people reviewing the grant that there is no possibility you won’t succeed. Incremental science tends to be favored in times like this because it’s safe. New ideas and di?cult or ground-breaking experiments, on the other hand, have a much harder time being supported. Well, one thing that is certain is that my parents - and their entire generation - were shaped by that experience as by nothing else in their lives. Even World War II didn’t have the e?ect that ten years of worrying about the essentials (food, clothing, shelter) did. Sixty years after the post-war recovery (and both of them lived to see the millennium turn), they were still ultra-conservative with Now, this may sound like I’m being critical of the bureaucrats who run the funding agencies, but actually, money, wasted not a scrap of food, and never believed I’m not. For the most part, they don’t make funding that good fortune was anything but a temporary