Ruthenium(III) Chloride Catalyzed Acylation of Alcohols, Phenols, and Thiols in Room Temperature Ionic Liquids 英文参考文献.docVIP

Molecules 2009, 14, 3528-3537; doi:10.3390/moleculeOPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article Ruthenium(III) Chloride Catalyzed Acylation of Alcohols, Phenols, and Thiols in Room Temperature Ionic Liquids Zhiwen Xi 1, Wenyan Hao 1, Pingping Wang 2 and Mingzhong Cai 1,* 1 Department of Chemistry, Jiangxi Normal University, Nanchang 330022, China; E-mails: xizhiwen1983@163.com (Z.X.); wenyanhao@ (W.H.) 2 Department of Chemistry, Jiujiang University, Jiujiang 332000, China; E-mail: wpp9090@ (P.W.) * Author to whom correspondence should be addressed; E-mail: caimzhong@163.com; Tel./Fax: +86 7918120388. Received: 3 July 2009; in revised form: 10 September 2009 / Accepted: 10 September 2009 / Published: 10 September 2009 Abstract: Ruthenium(III) chloride-catalyzed acylation of a variety of alcohols, phenols, and thiols was achieved in high yields under mild conditions (room temperature) in the ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim][PF6]). The ionic liquid and ruthenium catalyst can be recycled at least 10 times. Our system not only solves the basic problem of ruthenium catalyst reuse, but also avoids the use of volatile acetonitrile as solvent. Keywords: acylation; ruthenium; ionic liquid; green chemistry Introduction The development of environmentally friendly synthetic procedures has become a major concern throughout the chemical industry due to continuing depletion of natural resources and growing environmental awareness [1-4]. One of the prime concerns of industry and academia is the search for replacements for environmentally damaging organic solvents used on a large scale, especially those which are volatile and difficult to contain. Room temperature ionic liquids, especially those based upon the 1,3-dialkylimidazolium cation, have attracted growing interest in the last few years [5-9]. They offer a possible altern