Sequencing of Seven Haloarchaeal Genomes Reveals Patterns of Genomic Flux 英文参考文献.docVIP

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Sequencing of Seven Haloarchaeal Genomes Reveals Patterns of Genomic Flux 英文参考文献.doc

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Sequencing of Seven Haloarchaeal Genomes Reveals Patterns of Genomic Flux 英文参考文献

SequencingofSevenHaloarchaealGenomesReveals PatternsofGenomicFlux ErinA.Lynch1,MorganG.I.Langille2,AaronDarling3,ElizabethG.Wilbanks1,CaitlinHaltiner4,5, KatieS.Y.Shao6,MichaelO.Starr14,ClotildeTeiling7,TimothyT.Harkins8,RobertA.Edwards9,10,11, JonathanA.Eisen1,3,12,13*,MarcT.Facciotti1,3,14 * 1MicrobiologyGraduateGroup,UniversityofCaliforniaDavis,Davis,California,UnitedStatesofAmerica,2FacultyofComputerScience,DalhousieUniversity,Halifax, NovaScotia,Canada,3GenomeCenter,UniversityofCaliforniaDavis,Davis,California,UnitedStatesofAmerica,4Children’sHospitalOaklandResearchInstitute,Oakland, California, United States of America, 5Department of Forensic Science, University of California Davis, Davis, California, United States of America, 6Davis Senior High School,Davis,California,UnitedStatesofAmerica,7454LifeSciences,aRocheCompany,Branford,Connecticut,UnitedStatesofAmerica,8LifeTechnologies,Beverly, Massachusetts,UnitedStatesofAmerica,9DepartmentofComputerScience,SanDiegoStateUniversity,SanDiego,California,UnitedStatesofAmerica,10Department ofBiology,SanDiegoStateUniversity,SanDiego,California,UnitedStatesofAmerica,11DivisionofMathematicsandComputerScience,ArgonneNationalLaboratory, Argonne, Illinois, United States of America, 12Department of Evolution and Ecology, University of California Davis, Davis, California, United States of America, 13Department of Medical Microbiology and Immunology, University of California Davis, Davis, California, United States of America, 14Department of Biomedical Engineering,UniversityofCaliforniaDavis,Davis,California,UnitedStatesofAmerica Abstract Wereportthesequencingofsevengenomesfromtwohaloarchaealgenera,HaloferaxandHaloarcula.Easeofcultivation and the existence of well-developed genetic and biochemical tools for several diverse haloarchaeal species make haloarchaeaamodelgroupforthestudyofarchaealbiology.Theuniquephysiologicalpropertiesoftheseorganismsalso makethemgoodcandidatesfornovelenzymediscoveryforbiotechnologicalapplication