Serological Studies of Neurologic Helminthic Infections in Rural Areas of Southwest Cameroon Toxocariasis, Cysticercosis and Paragonimiasis 英文参考文献.docVIP

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Serological Studies of Neurologic Helminthic Infections in Rural Areas of Southwest Cameroon Toxocariasis, Cysticercosis and Paragonimiasis 英文参考文献.doc

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Serological Studies of Neurologic Helminthic Infections in Rural Areas of Southwest Cameroon Toxocariasis, Cysticercosis and Paragonimiasis 英文参考文献

SerologicalStudiesofNeurologicHelminthicInfections inRuralAreasofSouthwestCameroon:Toxocariasis, CysticercosisandParagonimiasis AgatheNkouawa1,2,YasuhitoSako1,SonoyoItoh1,AlidaKouojip-Mabou3,ChristNade`geNganou4, YasuakiSaijo5,JennyKnapp1,HiroshiYamasaki6,MinoruNakao1,KazuhiroNakaya7,RogerMoyou- Somo2,4,AkiraIto1* 1DepartmentofParasitology,AsahikawaMedicalCollege,Asahikawa,Hokkaido,Japan,2MedicalResearchCenter,InstituteofMedicalResearchandMedicinalPlants Studies(IMPM),MinistryofScientificResearchandInnovation,Yaounde′, Cameroon,3Cite′ desPalmiersHealthDistrict,Douala,Cameroon,4DepartmentofParasitology andInfectiousDiseases,FacultyofMedicineandBiomedicalSciences,UniversityofYaoundeI,Yaounde′,Cameroon,5DivisionofCommunityMedicineandEpidemiology, DepartmentofHealthScience,AsahikawaMedicalCollege,Asahikawa,Hokkaido,Japan,6DepartmentofParasitology,NationalInstituteofInfectiousDiseases,Tokyo, Japan,7AnimalLaboratoryforMedicalResearch,AsahikawaMedicalCollege,Asahikawa,Hokkaido,Japan Abstract Background: Bothepilepsyandparagonimiasis hadbeenknowntobe endemicin SouthwestCameroon.Atotalof188 people (168 and 20 with and without symptoms confirmed by clinicians, respectively, 84.6% under 20 years old) were selected on a voluntary basis. Among 14 people (8.3%) with history of epilepsy, only one suffered from paragonimiasis. Therefore, we challenged to check antibody responses to highly specific diagnostic recombinant antigens for two other helminthic diseases, cysticercosis and toxocariasis, expected to be involved in neurological diseases. Soil-transmitted helminthicinfectionswerealsoexamined. Methodology/Principal Findings: Fecal samples were collected exclusively from the 168 people. Eggs of Ascaris lumbricoides, Trichuris trichiura and hookworms were found from 56 (33.3%), 72 (42.8%), and 19 (11.3%) persons, respectively.Serologyrevealedthat61(36.3%),25(14.9%)and2(1.2%)of168personsshowedspecificantibodyresponses to toxocariasis, paragonimiasis and cysticercosis, res