Smoking Cessation and Cardiovascular Disease Risk Factors Results from the Third National Health and Nutrition Examination Survey 英文参考文献.docVIP

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Smoking Cessation and Cardiovascular Disease Risk Factors Results from the Third National Health and Nutrition Examination Survey 英文参考文献.doc

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Smoking Cessation and Cardiovascular Disease Risk Factors Results from the Third National Health and Nutrition Examination Survey 英文参考文献

o Openaccess,freelyavailableonline PL S MEDICINE SmokingCessationandCardiovascularDisease RiskFactors:ResultsfromtheThirdNational HealthandNutritionExaminationSurvey Arvind Bakhru1,2*,Thomas P.Erlinger 3,4,5 1University of Rochester Medical Center, School of Medicine, Rochester, New York, United States of America, 2Department of Epidemiology and Public Health, Yale UniversitySchoolofMedicine,NewHaven,Connecticut,UnitedStatesofAmerica, 3DepartmentofEpidemiology,JohnsHopkinsUniversityBloombergSchoolofPublic Health, Baltimore, Maryland, United States of America, 4Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America,5WelchCenterforPrevention,Epidemiology,andClinicalResearch,JohnsHopkinsMedicalInstitutions,Baltimore,Maryland,UnitedStatesofAmerica ABSTRACT CompetingInterests:Theauthors havedeclaredthatnocompeting interestsexist. Background AuthorContributions:ABandTPE designedthestudy.ABanalyzed thedata.ABandTPEcontributed Cigarette smoking is a major risk factor for the development and progression of towritingthepaper. cardiovascular disease. While smoking is associated with increased levels of inflammatory markers and accelerated atherosclerosis, few studies have examined the impact of smoking cessation on levels of inflammatory markers. The degree and rate at which inflammation subsidesaftersmokingcessationareuncertain.Italsoremainsunclearastowhethertraditional risk factors can adequately explain the observed decline in cardiovascular risk following smokingcessation. AcademicEditor:AlanDLopez, UniversityofQueensland, Australia Citation:BakhruA,ErlingerTP (2005)Smokingcessationandcar- diovasculardiseaseriskfactors: ResultsfromtheThirdNational HealthandNutritionExamination survey.PLoSMed2(6):e160. MethodsandFindings Using data from 15,489 individuals who participated in the Third National Health and NutritionExaminationSurvey(NHANESIII),weanalyzedtheassociationbetweensmokingand smokingcessationonle