The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis 英文参考文献.docVIP

Available online /content/10/3/R67 Research article Open Access Vol 10 No 3 The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis Rieke Alten1, Hermann Gram2, Leo A Joosten3, Wim B van den Berg3, Joachim Sieper4, Siegfrid Wassenberg5, Gerd Burmester6, Piet van Riel7, Maria Diaz-Lorente8, Gerardus JM Bruin8, Thasia G Woodworth8, Christiane Rordorf8, Yannik Batard8, Andrew M Wright8 and Thomas Jung8 1Department of Internal Medicine II, Rheumatology, Schlosspark-Klinik Teaching Hos