TREC-Rio trial a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243] 英文参考文献.docVIP

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TREC-Rio trial a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243] 英文参考文献.doc

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TREC-Rio trial a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243] 英文参考文献

BMC Psychiatry BioMedCentral Open Access BMC2002Psychiatry, 2 Study protocol x TREC-Rio trial: a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCT Gisele Huf*1, Evandro SF Coutinho1 and Clive E Adams2 Address: 1Oswaldo Cruz Foundation – FIOCRUZ, Av. Brasil, 4635 – Manguinhos, Rio de Janeiro – Brazil and 2The Cochrane Schizophrenia Group, Academic Unit of Psychiatry and Behavioural Sciences, University of Leeds, 15 Hyde Terrace, Leeds, LS2 9LT, UK E-mail: Gisele Huf* - gisele@ensp.fiocruz.br; Evandro SF Coutinho - evandro@ensp.fiocruz.br; Clive E Adams - ceadams@ *Corresponding author Published: 16 October 2002 Received: 11 April 2002 Accepted: 16 October 2002 BMC Psychiatry 2002, 2:11 This article is available from: /1471-244X/2/11 ? 2002 Huf et al; licensee BioMed Central Ltd. This article is published in Open Access: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the articles original URL. Abstract Background: Agitated or violent patients constitute 10% of all emergency psychiatric treatment. Management guidelines, the preferred treatment of clinicians and clinical practice all differ. Systematic reviews show that all relevant studies are small and none are likely to have adequate power to show true differences between treatments. Worldwide, current treatment is not based on evidence from randomised trials. In Brazil, the combination haloperidol-promethazine is frequently used, but no studies involving this mix exist. Methods: TREC-Rio (Tranquiliza??o Rápida-Ensaio Clínico [Translation: Rapid Tranquillisation- Clinical Trial]) will compare midazolam with haloperidol-promethazine mix for treatment of agitated patients in emergency psychiatric rooms of Rio de Janeiro, Brazil. TREC-Rio is a randomised, controlled, pragm