Usefulness of procalcitonin for diagnosis of sepsis in the intensive care unit 英文参考文献.docVIP

Available online /content/7/1/85 Open Access Research Usefulness of procalcitonin for diagnosis of sepsis in the intensive care unit v v Canan BalcI1, Hülya Sungurtekin2, Ercan Gürses3, Ugur Sungurtekin4 and Bünyamin Kaptanoglu5 1Specialist, Department of Anesthesiology and Reanimation, Pamukkale Unversity School of Medicine, Denizli, Turkey 2Associate Professor, Department of Anesthesiology and Reanimation, Pamukkale Unversity School of Medicine, Denizli, Turkey 3Assistant Professor, Department of Anesthesiology and Reanimation, Pamukkale Unversity School of Medicine, Denizli, Turkey 4Professor, Department of General Surgery, Pamukkale Unversity School of Medicine, Denizli, Turkey 5Associate Professor, Department of Biochemistry, Pamukkale Unversity School of Medicine, Denizli, Turkey Correspondence: Hülya Sungurtekin, hsungurtekin@ Received: 10 June 2002 Critical Care 2003, 7:85-90 (DOI 10.1186/cc1843) This article is online at /content/7/1/85 Revisions requested: 31 July 2002 Revisions received: 28 August 2002 Accepted: 5 October 2002 I ? 2003 Balc et al., licensee BioMed Central Ltd (Print ISSN 1364-8535; Online ISSN 1466-609X). This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any non-commercial purpose, provided this notice is preserved along with the articles original URL. Published: 30 October 2002 Abstract Introduction The diagnosis of sepsis in critically ill patients is challenging because traditional markers of infection are often misleading. The present study was conducted to determine the procalcitonin level at early diagnosis (and differentiation) in patients with systemic inflammatory response syndrome (SIRS) and sepsis, in comparison with C-reactive protein, IL-2, IL-6, IL-8 and tumour necrosis factor-α. Method Thirty-three intensive care unit patients were diagnosed with SIRS, se