原创力文档Application of a pig ligated intestinal loop model for early Lawsonia intracellularis infection.docVIP
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Application of a pig ligated intestinal loop model for early Lawsonia intracellularis infection
Boutrupetal.ActaVeterinariaScandinavica2010,52:17
/content/52/1/17
RESEARCH
OpenAccess
Applicationofapigligatedintestinalloopmodel
forearlyLawsoniaintracellularisinfection
TorstenSBoutrup1,2,KirstenSchauser3,J?rgenSAgerholm2,TimKJensen1*
Abstract
Background:Porcineproliferativeenteropathyinpigsiscausedbytheobligate,intracellularbacteriumLawsonia
intracellularis.Invitrostudieshaveshownclosebacterium-cellinteractionfollowedbycellularuptakeofthe
bacteriumwithin3hpostinoculation(PI).However,knowledgeoftheinitialinvivointeractionbetweenporcine
intestinalepitheliumandthebacteriumislimited.Theaimsoft
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