Application of in vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis.docVIP

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Application of in vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis.doc

Application of in vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis

Mohanetal.ArthritisResearchTherapy2011,13:R210 /content/13/6/R210 RESEARCH ARTICLE OpenAccess Applicationofinvivomicro-computed tomographyinthetemporalcharacterisationof subchondralbonearchitectureinaratmodelof low-dosemonosodiumiodoacetate-induced osteoarthritis GeethaMohan1,2*,EgonPerilli1,2,JuliaSKuliwaba1,2,JuliaMHumphries1,2,IanHParkinson1,2 and NicolaLFazzalari1,2 Abstract Introduction:Osteoarthritis(OA)isacomplex,multifactorialjointdiseaseaffectingboththecartilageandthe subchondralbone.AnimalmodelsofOAaidintheunderstandingofthepathogenesisofOAandtestingsuitable drugsforOAtreatm

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Application of in vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis.docVIP