Assessment and histological analysis of the IPRL technique for sequential in situ liver biopsy.docVIP

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Assessment and histological analysis of the IPRL technique for sequential in situ liver biopsy.doc

Assessment and histological analysis of the IPRL technique for sequential in situ liver biopsy

Roweetal.ComparativeHepatology2011,10:7 /content/10/1/7 RESEARCH OpenAccess AssessmentandhistologicalanalysisoftheIPRL techniqueforsequentialinsituliverbiopsy AnthonyRowe1,LillianZhang1,AzmenaHussain1,FilipBraet2andIqbalRamzan1* Abstract Background:Theisolatedperfusedratliver(IPRL)isatechniqueusedinawiderangeofliverstudies.Typically liversareassessedattreatmentendpoint.Techniqueshavebeendescribedtobiopsyliverintheliveratandpost- hepatectomy. Results:Thispaperdescribesatechniqueforobtainingtwofullandonepartiallobebiopsiesfromtheliverinsitu duringanIPRLexperiment.Ourapproachofretainingtheliver

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