分子生物学（张海红）CHAPTER 13.pptVIP

Chapter 13RNA Splicing Most of the eukaryotic genes are mosaic (嵌合体), consisting of intervening sequences separating the coding sequence Exons (外显子): the coding sequences Introns (内含子) : the intervening sequences RNA splicing: the process by which introns are removed from the pre-mRNA. Alternative splicing (可变剪接): some pre-mRNAs can be spliced in more than one way , generating alternative mRNAs. 60% of the human genes are spliced in this manner. RNA splicing Alternative splicing RNA editing mRNA transport RNA splicing Chemistry of RNA splicing The splicesome machinery Splicing pat