分子生物学（张海红）CHAPTER 16.pptVIP

* Figure 11.10 shows that there are two immediate early genes, N and cro, which are transcribed by host RNA polymerase. N is transcribed toward the left, and cro toward the right. Each transcript is terminated at the end of the gene. pN is the regulator that allows transcription to continue into the delayed early genes. It is an antitermination factor that suppresses use of the terminators tL and tR. (Its mechanism is discussed in 9 Transcription.) In the presence of pN, transcription continues to the left of N into the recombination genes, and to the right of cro into the replication genes.