Cerebral blood flow quantification in the rat a direct comparison of arterial spin labeling MRI with radioactive microsphere PET.docVIP

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Cerebral blood flow quantification in the rat a direct comparison of arterial spin labeling MRI with radioactive microsphere PET.doc

Cerebral blood flow quantification in the rat a direct comparison of arterial spin labeling MRI with radioactive microsphere PET

Bo′setal.EJNMMIResearch2012,2:47 /content/2/1/47 ORIGINAL RESEARCH OpenAccess Cerebralblood?owquanti?cationintherat:a directcomparisonofarterialspinlabelingMRI withradioactivemicrospherePET AgnieszkaBo′s1*,RalfBergmann1,KlausStrobel2,FrankHofheinz1,Jo¨rgSteinbach1andJo¨rgvandenHo?1 Abstract Background: Arterialspinlabelingmagneticresonanceimaging(ASL-MRI)hasbeenrecognisedasavaluable methodfornon-invasiveassessmentofcerebralblood?owbutvalidationstudiesregardingquanti?cationaccuracy bycomparisonagainstanacceptedgoldstandardarescarce,especiallyinsmallanimals.Wehaveconductedthe presentstudywith

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Cerebral blood flow quantification in the rat a direct comparison of arterial spin labeling MRI with radioactive microsphere PET.docVIP