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Extracorporeal life support for status asthmaticus the breath of life thats often forgotten
Available online /content/13/2/136
Commentary
Extracorporeal life support for status asthmaticus: the breath of
life that’s often forgotten
Nana Ekua Coleman and Heidi J Dalton
Department of Critical Care Medicine, Children’s National Medical Center, The George Washington University School of Medicine, Washington,
DC 20010, USA
Corresponding author: Heidi J Dalton, hdalton@
Published: 28 April 2009
Critical Care 2009, 13:136 (doi:10.1186/cc7757)
This article is online at /content/13/2/136
? 2009 BioMed Central Ltd
See related research by Hebbar et al., /content/13/2/R29
Abstract
ECLS they had a serum pH of less than 7.0, an arterial
carbon dioxide tension (PaCO2) above 120 torr, and an
arterial oxygen tension above 50 torr. The percentage of
patients in whom venovenous (VV) cannulation was used was
higher in the Egleston group than in the ELSO group (92%
versus 82%), but over time more patients underwent VV
Status asthmaticus continues to be significant cause of intensive
care admission, morbidity, and mortality in pediatric populations.
Furthermore,
despite improved outpatient management and
broader use of controller medications, patients with severe status
asthmaticus account for a notable proportion of these admissions.
is variability in management and outcomes between
There
cannulation.
Despite these demographic characteristics,
institutions; however, early and aggressive management to avoid
respiratory failure is paramount. In those patients who progress to
develop severe respiratory failure, extracorporeal life support
(ECLS) can be a life-saving therapy. Here, we briefly overview the
use of ECLS for status asthmaticus, as reported through the
Extracorporeal Life Support Organization, including the specific
institutional experience at Children’s Healthcare of Atlanta at
Egleston, and consider how earlier initiation o
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