新型磁场场流分离体系的构建和评价.pdfVIP

hydrodynamic lift force balance the particles in a particular stream layer. Being closer to the center of the capillary tube, the weakly magnetic particles have a shorter retention time, and thus can be separated with the strong magnetic particles. The resolution effect improves a lot at high flow speed, in which the comparatively large lift force can eliminate the irreversible adsorption and aggregation. The resolution of the method is related to parameters such as the fluid velocity, magnetic density and the number of magnet in the static magnetic field .And in the rotary magnetic field different susceptibility of magnetic particles could be separated best when the rotating frequency was 2.21 Hz, the flow rate was 0.16 mL/min and the distance of magnetic field was 2 mm. Magnetic particles of different sizes or different magnetic susceptibilities can be separated successfully in the static or rotary magnetic field and the rotary system has a big advantage over the static one in both the separation efficiency and flexible operations. In this article, the methods which applied two different modes of magntic field flow fractionation can successfully separate different magnetic susceptibility particles. The article provide a viable mean for separating magnetic sample with different magnetic susceptibility and determing the distribution of magnetic susceptibility. And it also bring up a new idea for application of magntic field flow fractionation and separation and determination of magnetic pharmaceutical formulation. Key words: field flow fractionation; magnetic field flow fractionation; magnetic susceptibility; magnetic particles 目 录 第一章 文献综述1