掉常反应分类(国外英文资料).docVIP

变态反应分类(国外英文资料) Ⅰ type of allergy Fast hairstyle (Ⅰ allergy), also known as allergic reaction allergens after entering the body, B cells induced IgE antibodies. IgE has a high affinity with the target cell, which binds strongly to the surface of the mast cell, basophilic cells. When the same antigen sensitization to once again into the body, combined with IgE antibody, will cause a series of biochemical reaction of the cell membrane, begin the process of two parallel happen: degranulation and synthesis of new media. 1) mast cell degranulation changes with the basophilic granulocyte, releasing many active medium from the particles, such as histamine, proteolytic enzyme, heparin, chemokines, etc; At the same time, the phospholipid degradation of the membrane of the cell membrane releases the peanut tetraenoic acid. Its metabolized in two ways, and its synthetic prostaglandin and thrombus A2; And white blood cell triene (LTs), platelet activation factor (PAF). All kinds of medium to spread to the whole body, along with blood stream function in effect organs such as skin, mucous membranes, respiratory tract, cause the small blood vessels and capillaries expansion, the increase of blood capillary permeability, smooth muscle contraction, gland secretion to increase, acidophilic granulocyte increased, infiltration, can cause allergy skin and mucosa (urticaria, eczema, angioneurotic oedema), respiratory allergic reaction (allergic rhinitis and bronchial asthma, laryngeal edema), digestive tract allergies (food allergic gastroenteritis), systemic hypersensitivity (anaphylactic shock), summary: because the IgE is much by mucosa secretion, so I caused more mucosa reaction. Ⅱ type of allergy The cytotoxic (Ⅱ allergy) antibodies (IgG and a few more for IgM and IgA) first adsorbed on the membrane surface antigen composition or the cells themselves composition, combining then kill target cells through four different channels. (1) antibodies and complement mediated cytolysis: IgG/I