2-(3-4-5-三甲氧基苯基)-1-3-二噻烷的合成-本科论文.docVIP

本科毕业论文 题 目： 学 院： 专 业： 学 号： 学生姓名： 指导教师： 职 称： 年月日 SnCl2·2H2O）为催化剂，催化剂量与原料3,4,5-三甲氧基苯甲醛的摩尔比为0.05:1，35℃条件下反应0.6h，得率可稳定达到99%以上。产物结构通过FT-IR、GC-MS等进行表征。 关键词3,4,5-三甲氧基苯甲醛；1,3-丙二硫醇；硫缩醛；合成；工艺条件  Synthesis of 2-(3,4,5-trimethoxyphenyl)-1,3-dithiane Abstract The exploration seeking for safe,efficient,green,with a novel mechanism of action and environment-friendly pesticides has become the hotspots of the pesticides research and development all over the world. Synthesising the new 1,3-dithiane derivatives maybe excogitated low toxicity ,green,new and efficient pesticides. In this paper,the raw material 3,4,5-trimethoxybenzaldehyde was synthesized 2-(3,4,5-trimethoxyphenyl)-1,3-dithian by thioacetalization with dimercaptopropane.By exploring of the factors about Solvents type ,catalyst type ,catalyst dosage,reaction time,material ratio, reaction temperature on the synthesis of 2-(3,4,5-trimethoxyphenyl)-1,3-dithiane,we can determine the optimum conditions: ethanol as solvent and tin chloride dihydrate(SnCl2·2H2O) as catalyst,molar ratio of catalyst dosage and 3,4,5-trimethoxybenzaldehyde is 0.05:1,molar ratio of 3,4,5-trimethoxybenzaldehyde and 1,3-dimercaptopropane is 1:1.2, the reaction temperature is 35 ℃and the reaction time is 0.6 hour, the yield can reach more than 99% stable.The structure of was determined by FT-IR, GC-MS and so on. Key words: 3,4,5-trimethoxybenzaldehyde; 1,3-dimercaptopropane; synthesis; 2-(3,4,5- trimethoxyphenyl)-1,3-dithiane; yield；process conditions 目 录 1 前言 1 1.1 课题的来源、依据及意义 1 1.2文献综述 1 1.2.1 1,3-丙二硫醇的物化性质及应用 2 1.2.2 3,4,5-三甲氧基苯甲醛的概述 2 1.2.2.1 3,4,5-三甲氧基苯甲醛的来源 2 1.2.2.2 3,4,5-三甲氧基苯甲醛的物化性质 5 1.2.2.3 3,4,5-三甲氧基苯甲醛的应用 5 1.3 二噻烷类化合物的性质及应用 7 1.3.1 二噻烷类化合物的性质 7 1.3.2 二噻烷类化合物的应用 7 1.4 2-(3,4,5-三甲氧基苯基)-1,3-二噻烷的研究现状 9 1.5 本论文的研究内容 10 2 2-(3,4,5-三甲氧基苯基)-1,3-二噻烷的合成 10 2.1 实验部分 10 2.1.1 原料、试剂与仪器 10 2.1.2 反应式 11 2.1.3 反应机理 11 2.