肝脏恶性病变诊断模型和肝切除术后肝衰预测模型的建立.pdfVIP

Building of mode diagnosing liver malignancy and mode predicting posthepatectomy liver failure Object: to explore the joint application of a number of tumor markers in the diagnosis of hepatic malignant lesions and establish the diagnostic formula; to evaluate liver failure incidence after hepatectomy by using the commonly liver function examination, and estabilish a prediction formula. Methods : 99 patients with hepatectomy admited in the Affiliated Hospital of LuZhou Medical College between April 1 2009 to December 31 2011 were enrolled in this study. (1)99 patients was divided into benign disease group and malignancy disease group according to pathological diagnosis, alpha-fetoprotein, carcinoembryonic antigen, carbohydrate antigen 19-9, alpha-fucosidase, serum ferritin were compared by using the Wilcoxon rank sum test between two groups and statistical difference variables was entered into the logistic regression model after natural logarithmic transformation and established a formula predicting malignant hepatic lesions, the model would be evaluated by using ROC curve . (2) 99 patients was divided into liver failure group and the non-liver failure group according posthepatectomy recovery. Demographics characteristic , liver function, renal function, blood lipids, blood routine examination , electrolytes, coagulation, surgical situation, and other projects was compared by t test, χ2 test, rank sum test between the two groups before hepatectomy, statistically different projects were entered in the logistic regression model and established a formula predicting liver failure after hepatectomy, the model was be tested by ROC curve to evaluate the diagnost