胆碱r阻断药09麻醉、生物.pptVIP

* * Chapter 8 胆碱受体阻断剂（I） －M-R阻断剂 Cholinoceptor blocking drugs － M-R blocking drugs Instructional objectives 1. 阐述阿托品的作用、用途、不良反应、禁忌症； 2.比较山莨菪碱和东莨菪碱的作用特点及用途； 3.列举阿托品的合成代用品 4.列举肌松药的分类及代表药 M-R阻断药 muscarinic blocking drugs 抗胆碱药 anticholinegics. 副交感神经阻断药 parasympatholytics Muscarinic blocking drugs have no intrinsic activity, and they can produce effects only by blocking the activation of muscarinic receptors by muscarinic agonists or by neuronally released ACh. § 1 阿托品和阿托品类生物碱 Atropine ＆ atropine-like alkaloid 存在于颠茄 、曼陀罗、莨菪中 颠茄 Atropa b