壳聚糖纳米混悬剂的研制和表征.pdfVIP

中国组织工程研究与临床康复第12 :ii些第14 J/IJ 2∞8-ω币。1 出版 @走元走基础 Joumal 01Clinical Rehabilitalive Ttssue Enginee阳g Research Aprill.2008 Vol.12. No.14 壳聚糖纳米混悬剂的研制和表征** 蒋玉燕，毕忆群，房固坚，蒋建国 Preparation and characteris创CS ofchit翩翩翩nosuspensions Jiang YUγan，自i Yi-qun , Fang Guo-jian , Jiang Jian-guo Institu阳 d Abstrad: 叽le experiment was 仰rfonned in the Insti阳忧。f Bioengine衍ing， Zhejiang Academy of Medícal Sciences from July Bioengin儒巾唱. 2∞610 June 2∞7. Chitosan (87.859岛 deacetylation degree , 195 mPa S viscosity , 7.1 3 % moisture content, 0.82% ash content, and zh句iang Academy of batch number 0506211ω)wωoffered by Zhejiang Golden‘ shell Bíochemical CO.，Lω. Chitosan nanoparticles were produced by Medical Scien帽仇 means of physico-chemical methods , such a南 chemical acídolysís，酣Co { radíation , autoclave, ultrωonic wave and stabilizing 皿g泊。u 31∞13. Zheji捕事 agent. Transmission eloctron microscopy rev侃l创由at chitosan nanoparticles were sphere, and laser dynamic light scat忧ring 阶uviDce， α由咀 instrument showed 出由e average diameter of 由e prepared nanoparticles was 25.3 nm , accounting for 99.1% of由eω凶 particles， ωd narrow distribution índicated consis阳t sÎze of the particles. It ís feasible to prepare chi刷an nanosuspensíons by the primary Jiang Yu-y四. method ofωCo ( radíation. which ís convenient, fast, pollution耐隙， and reproducible. A耐心cia加 investigator. 阳皿i阳.te of Bioengíneering. Jiang yy, Bi YQ , Fang GJ, liang JG. Preparation and characteristics of chiωsan nanosuspensions.Zhongguo Zuzhi Gongcheng Zhejiang Academy 01 Medícal Scíeøo剧， Yanjiu 阳Linch刷刷g Kangω2008;12(14):2628部30 [lzglck闷。umallupfilesl08-14/14k-2628(ps).pdf) Hang刷刷 31∞13. Zltejiang 摘要 Provin~. China 背攒s 实验-r 2(刷刊阴阳制在浙江省医学科学院生物工穗研究所完成。究聚糖(脱乙酸度为 87.85~品，盖世度为 195 mPa 喻， Jlan仕yuyan