DiseasesinPoland剖析.PDFVIP

International Journal of Environmental Research and Public Health Article Oral Health Status of Patients with Lysosomal Storage Diseases in Poland ˙ 1 2 3 3 Damian Dra˛zewski , Małgorzata Grzymisławska , Katarzyna Korybalska , Natasza Czepulis , Marian Grzymisławski 4, Janusz Witowski 3, * and Anna Surdacka 1 1 Department of Conservative Dentistry and Periodontology, Poznan University of Medical Sciences, 60-812 Poznan, Poland; damian.stom@ (D.D.); annasurd@ (A.S.) 2 Department of Anatomy, Poznan University of Medical Sciences, 61-781 Poznan, Poland; malgorzatagrzymislawska@.pl 3 Department of Pathophysiology, Poznan University of Medical Sciences, 60-806 Poznan, Poland; koryb@.pl (K.K.); czepulis@.pl (N.C.) 4 Department of Metabolic Disease, Nutrition and Internal Medicine, Poznan University of Medical Sciences, 60-355 Poznan, Poland; mariangrzym@.pl * Correspondence: jwitow@.pl Academic Editor: Paul B. Tchounwou Received: 16 January 2017; Accepted: 2 March 2017; Published: 9 March 2017 Abstract: Patients with lysosomal storage diseases (LSDs) suffer from physical and mental disabilities, which together with poor access to professional care may lead to impaired oral health. This cross-sectional case-control study characterized the status of oral health in patients with LSDs in Poland. Thirty-six children and young adults with various forms of LSDs were examined. The data were compared with those from age- and sex-matched healthy controls. Exemplary cases were presented to highlight typical problems in oral care associated with LSDs. When possible, saliva was collected and analyzed for total protein, inflammatory mediators, and antioxidant status.