9MRSA感染2008年抗菌药物学习班讲义-培训课件.pptVIP

* * * * * * * * * * * * * * * 130 12 healthy adult males participated in a double blind, randomised, two-way cross over study to determine histamine release and frequency/severity of Red man syndrome. 11/12 subjects experienced Red Man syndrome while receiving 万古霉素. The development of 万古霉素 induced Red Man syndrome was accompanied by an increase in histamine concentrations in plasma which returned to baseline within 1h of discontinuation of the infusion. No subject experienced histamine release or Red Man syndrome as a result of 替考拉宁 administration. In larger 替考拉宁 surveillance studies, th