呃效牮歩湲丠敩獬湥-StatisticalAnalysisof.pptVIP

The DNA Array Analysis Pipeline Example: Batch to batch variation Example: Data analysis - Blocking We can capture the batch variation by blocking Ex: Result of the 2-way ANOVA(3 p-values) Conclusion Array data contains stochastic noise Therefore statistics is needed to conclude on differential expression We can’t really trust the p-value But the statistics can rank genes The capacity/needs of downstream processes can be used to set cutoff FDR can be estimated t-test is used for two category tests ANOVA is used for multiple categories * Statistical Analysis of Microarray Data By H. Bj?rn N