IAP和ACS定义和病理生理.pdf

Definitions and Pathophysiological Implications of Intra-abdominal Hypertension and Abdominal Compartment Syndrome MANU L. N. G. MALBRAIN, M.D., PH.D.,» MICHAEL L. CHEATHAM, M.D.t From the *Intensive Care Unit, Ziekenhuis Netwek Antwerpen (ZNA), Antwerpen, Belgium; and the f Surgical Intensive Care Units, Orlando Regional Medical Center, Orlando, Florida For any syndrome or disease process, uniform definitions are essential to facilitate effective clinical communication as well as evaluation of the scientific literature and standardization of research. The following consensus definitions for intra-abdominal hypertension (IAH) and ab- dominal compartment syndrome (ACS) have been proposed by the World Society of the Ab- dominal Compartment Syndrome and are now widely accepted around the world. The use of these definitions, and their subsequent revisions as new evidence becomes published, will further improve communication and future research in this area. This review briefly addresses the present definitions as well as the pathophysiological effects of IAH/ACS on end-organ function. NTRA-ABDOMINAL HYPERTENSION (IAH ) an d abdomina l logical implications of IAH/ACS, are bdefiy discussed I compartment syndrome (ACS) have been increasingly here. recognized as causes of significant morbidity and mor- tality in critically ill medical and surgical patients. Al- Definitions though IAH is a continuum of progressively worsening organ dysfunction, ACS is an all or none phenomenon IAP is the steady-state