离心微流体生物医学的应用.pdfVIP

View Article Online / Journal Homepage / Table of Contents for this issue CRITICAL REVIEW /loc | Lab on a Chip Centrifugal microfluidics for biomedical applications Robert Gorkin,a Jiwoon Park,b Jonathan Siegrist,a Mary Amasia,a Beom Seok Lee,c Jong-Myeon Park,cd c c ab b Jintae Kim, Hanshin Kim, Marc Madou and Yoon-Kyoung Cho* Received 16th November 2009, Accepted 3rd March 2010 First published as an Advance Article on the web 28th May 2010 DOI: 10.1039/b924109d The centrifugal microfluidic platform has been a focus of academic and industrial research efforts for almost 40 years. Primarily targeting biomedical applications, a range of assays have been adapted on the system; however, the platform has found limited commercial success as a research or clinical tool. 2 Nonetheless, new developments in centrifugal microfluidic technologies have the potential to establish 1 D 0 9 wide-spread utilization of the platform. This paper presents an in-depth review of the centrifugal 2 r 0 e 1 microfluidic platform, while highlighting recent progress in the field and outlining the potential for b 4 m 2 9 e B future applications. An overview of centrifugal microfluidic technologies is presented, including v o / 9 descriptions of advantages of the platform as a microfluidic handling system and the principles behind N 3 0 5 1 2 0. centrifugal fluidic manipulation. The paper also discusses a history of significant centrifugal microfluidic n 1 o : i platf