雷帕霉素和紫杉醇药物洗脱支架治疗冠状动脉开口病变的临床疗效比较_陈珏.pdf

326 2007 10 22 5 ( 147 )ChineseCirculationJourna,lDecember2007, Vo.l22 No.5(SerialNo.147 ) · · 陈珏　陈纪林　乔树宾　徐波　杨跃进　高润霖　秦学文　李建军　袁晋青　姚民 吴永健　刘海波　 军　尤士杰＊ :。 : 2004 4 12 200 6 04 30 , 6 92 (95 )。 ( , Boston Taxus)45 (47 ) (, Cordis Cypher )47 (48)。、。 : 47 47 , 48 4 9 , 100%。 (2.85 ±0.53 )mm (2.96 ±0.4 1)mm, (15.7 ±14.1)mm(18.1 ±11.6)mm;(19.68 ±14.26 )mm(23.87 ±12.17 )mm, (14.2 ±2.9)atm(15.0±2.7)amt, 。 30 , 。 6 6.4% 11.1%, (=0.184 )。 〔(225 ±84 ) vs(210 ±50 )〕。 22.2%(10 /4 5) 15.5%(7 /4 5), 4.3%(2/47) 0%(0 /47), (0.01); 6.7%(3/4 5 ) 4.3%(2 /47 ), (0.05)。 6 8.9%, 4.3%, (0.05 )。 〔(0.65 ±0.67 )mm, (0.68 ± 0.65 )mm〕 〔(0.16 ±0.18)mm, (0.15 ±0.24 )mm(0.001)〕。 : 。 , 6。 　　　 ComparisionofEfficacyofTwoDrug-ElutingStentforOstialCoronaryLesion CHENJu,eCHENJi-lin, QIAOShu-bin, etal. DeparmtentofCoronaryHeartDiseas,eCardiovascularInstituteand FuWaiHospita,lCAMSandUMC, Beijing(100037 ), China Abstract Objective:Toevaluatetheclinicalefficacyandsafetyoftwodrug-elutingstentsinthetreatmentofostiallesionsofcoronary artery. Methods:FromApr.2004 toAp.r2006, 92 patientswith95 ostiallesionsofcoronaryarteryreceiveddrug-elutingstent.sAt 6 monthsafterprocedureangiographicfollow-upswereperformed, clinicalandinterventionaldatawereanalyzed. atientswere dividedintopaclitaxe-lelutingstentgroup(ESgroup, n=45, with47 lesions)andrapamycin-elutingstentsgroup(SESgroup, n=47, with4 8 lesions).Baselineclinicalcharacteristicsinbothgroupswerecomparable.Quantitativecoronaryangiography (QCA)wasperformedforallpatients.Themajoradversecardiovascularevents(MACE), includingdeath,smyocardialinfarc- tion(MI)andtargetlesionrevascularization(TLR)werecompared. Result:sThenumberofostialles