研究方向论文发表（节选）.PDFVIP

李硕，男，博士，副研究员。 2006 年7 月毕业于清华大学生物科学与技术系，获生物学专业生化与分子生 物学方向理学博士学位。2006 年 12 月至 2011 年 12 月在美国国立卫生研究院 （National Institutes of Health, NIH ）从事博士后研究，2012 年5 月通过人才引进 进入天津师范大学生命科学学院。2013 年入选天津市第二批“用三年时间引进 千名以上高层次人才”计划。现主持国家自然科学基金面上项目、天津市自然科 学基金及国家留学回国人员科研启动基金各一项，校级项目3 项。发表SCI 论文 30 余篇，累计影响因子超过100，累计他引500 余次。 研究方向： 1．胞外核苷（酸）信号在水生动物天然免疫、个体发育、逆境适应中的作用及 其分子机理。 2. 钙信号通路在水生动物逆境适应与天然免疫应答中的作用机制。 论文发表（节选）： 1. Shuo Li, Xiaoli Chen, Gaixiang Hao, Xuyun Geng, Wenbin Zhan, Jinsheng Sun. Identification and characterization of a novel NOD-like receptor family CARD domain containing 3 gene in response to extracellular ATP stimulation and its role in regulating LPS-induced innate immune response in Japanese flounder (Paralichthys olivaceus) head kidney macrophages. Fish Shellfish Immunology. 2016, 50:79-90. 2. Shuo Li, Xiaoli Chen, Xuyun Geng, Rongxin Lin, Ming Li, Jinsheng Sun. Molecular characterization of purinergic receptor P2X4 involved in Japanese flounder (Paralichthys olivaceus) innate immune response and its interaction with ATP release channel Pannexin1. Fish Shellfish Immunology. 2015, 47(1):100-109. 3. Shuo Li, Zirui Jia, Xiaoli Chen, Xuyun Geng, Jinsheng Sun. Identification and characterization of the cDNAs encoding the two subunits of Chinese mitten crab (Eriocheir sinensis) calcineurin: Their implications in stress and immune response. Fish Shellfish Immunology. 2015, 43(1):91-102. 4. Shuo Li, Xuejing Li, Xiaoli Chen, Xuyun Geng, Jinsheng Sun. ATP release channel Pannexin1 is a novel immune response gene in Japanese Flounder Paralichthys olivaceus . Fish Shellfish Immunology. 2014, 40(1):164-173. 5. Shuo Li, Xuejing Li, Claudio Coddou, Xuyun Geng, Junli Wei, Jinsheng Sun. Molecular characterization and expression analysis of ATP-gated P2