急性肺水肿(国外英文资料).docVIP

急性肺水肿 Acute pulmonary edema 1, the formation mechanism of pulmonary edema Qf = Kf[(Pmv - Ppmv) one delta f (PI MV one PI PMV)] Qf is the net filtration rate of liquid through the capillary wall per unit area per unit time; Kf is the coefficient of liquid filtration, and the amount of fluid through the capillary membrane when the unit pressure changes Delta f is a reflection coefficient (0.8), indicating that the pulmonary capillary membrane acts as a barrier to protein; 5mmHg pulmonary capillary hydrostatic pressure, normal value Pmv. Ppmv lung interstitial hydrostatic pressure, normal value - 7 mmHg. PI MV is plasma colloid osmotic pressure, normal value is 25 mmHg. PI PMV is the colloid osmotic pressure of lung tissue, the normal value is 12mmHg. Two. Mechanism of pulmonary edema (1) pulmonary capillary hydrostatic pressure (Pmv); (two) pulmonary interstitial colloid osmotic pressure (PI PMV); (three) pulmonary capillary colloid osmotic pressure (PI MV); (four) capillary permeability; 2 etiology and pathophysiology A hemodynamic pulmonary edema: is due to capillary hydrostatic pressure, and flow into the pulmonary interstitial fluid increased formation of pulmonary edema, but the permeability of protein molecules, all without any change or transfer liquid. Two permeability pulmonary edema is a common non cardiogenic pulmonary edema, not only lung water through the lung capillary endothelial cells surge, and the protein through the endothelial cells also increased. Hemodynamic pulmonary edema (I) cardiogenic pulmonary edema; (two) neurogenic pulmonary edema; (three) excessive fluid overload and pulmonary edema (four) pulmonary edema with pulmonary atelectasis (I) cardiogenic pulmonary edema; A variety of primary heart disease Right heart CO left heart CO The rapid increase of P m V in pulmonary blood. LVEDP 12mmHg PCWP 35mmHg, PVP 30mmHg Pm, V pi MV, Ppmv Acute pulmonary edema The main cause of left heart failure Left ventricular myocardial disease, such as co