英文校准0615--.docVIP

青岛市某区居民碘营养现状调查和 妊娠中期妇女甲状腺激素参考值范围探讨 在职研究生：封勇 专 业：免疫学 导 师：宋文刚 教授 李雅林 副教授 中文摘要 目的： 1、通过调查评估青岛市某区居民碘营养现况，指导本地居民科学合理补碘。 2、通过检测本地区妊娠中期妇女甲状腺功能指标，分析妊娠中期妇女甲状腺激素水平变化的特殊性，建立妊娠中期特异性血清促甲状腺激素（TSH）（FT3）（）P2.5表示下限，P97.5表示上限。 结果： 1、青岛市某区356例8～10周岁学龄儿童尿碘中位数为208.7μg/L，根据WHO/UNICEF/ICCIDD提出的尿碘中位数(200～299)μgμg/L，根据WHO/UNICEF/ICCIDD提出的尿碘中位数碘150μg/L为摄入不足的标准,为碘营养不足水平。 3、本地区妊娠中期妇女TSH中位数1.77mIU/L,参考值范围为（0.60～3.92）mIU/L；妊娠中期妇女FT4中位数12.62pmol/L,参考值范围为（9.10～16.21）pmol/L；妊娠中期妇女FT3中位数4.3pmol/L,参考值范围为（3.31～5.59）pmol/L。 结论 1、青岛市某区普通居民碘营养现况整体水平为碘营养充足水平，妊娠中期妇女碘营养状况整体水平为碘营养不足水平。因此，应加强不同人群的碘营养状况监测，科学合理的指导碘摄入。 2、建立了本地区正常妊娠中期妇女特异性甲状腺激素参考值范围，有利于妊娠期甲状腺功能异常疾病的正确诊断和及时治疗。 关键词：学龄儿童；妊娠期；碘营养状况；甲状腺功能 Investigation into Current Situation of Iodine Nutrition among Residents and discussion about the Thyroid Hormone Reference Range of Women in Mid Trimester Pregnancy and monitoring its functional parameter in H District, Qingdao On-the-job Postgraduate: Yong Feng Professional: Immunology Supervisor: Professor Wengang Song Associate professor Yalin Li Abstract Objective: 1.To moniter the iodine nutritional situation by assessing the level of iodine in urine,then to guide the the local residents taking in iodine in a scientific and reasonable way. 2.To analyze the particularity of the changing of thyroid hormones level in women in pregnancy ,then to establish the normal reference ranges of special serum TSH, FT3 and FT4 in mid trimester pregnancy. Methods: 1. The Investigation of current situation of iodine nutrition among residents(pupils) in H District, Qingdao. Sample 356 pupils from 8 to 10 years old from four subsidiary primary schools,included two urban schools, two township schools at random from Qingdao were investigated and use the method for determination of arsenic cerium catalytic spectrophotometry breadth (WS/T 107-2006) to measure urine iodine content randomly. Simultaneously, questionnaires were conducted on