一种简单的合成酰胺的方法_李维.pdfVIP

,Journalof AnhuiAgri. Sci.2009, 37( 15) :6845- 6846 李菲菲 况玲玲 李维, 郝玉芝, 李万亮, 张玉龙 (, 300130) [目的] 采用简单的合成方法来合成酰胺[方法]以L蛋氨酸和二胺(乙二胺, 1,6己二胺,六 哌嗪)为原料,无 乙醇为溶剂, 13 经过成盐反应, 热处理脱 生成成酰胺[结果]通过 C核磁共振谱, 红外光谱对产物进行了结构鉴定, 证明产品中存在酰胺键[结 论]蛋氨酸与二胺的摩尔量比为41, 热处理温度为130 , 热处理时间为6h 是最佳的反应条件, 产物的收率分别可达到96.0%92.0% 90.6% 13 C核磁共振; 红外光谱; 酰胺;简单合成方法 FQ202 A 0517- 6611(2009)15- 06845- 02 A Simple Synthetic Method of Amide LI Wei et al (School of Che icalEngineering andTechnology,Hebei University ofTechnology,Tianjin300130) Abstract [Objective] The research ai edto synthesizea ide by using a si ple synthesis ethod.[Method] WithL ethionine anddia ine co pounds (ethyl dia ine, 1,6hexa ethylenedia ine andpiperazine) as aterials andanhydrous alcohol assolvent,a idewassynthesized through salt for ing reac 13 tion and heat treat ent dehydration.[Result] The structures of thesynthetic a ide co poundswere deter ined by CNMR andIRspectra. It was proved that the product containeda ide.[Conclusion] The opti u olar ratiosofL ethionine anddia ine co poundswere41,the opti u heating te pera turewas 130 andthe opti u dehydration ti ewas6 hours.The yield of productswere about 96.0%,92.0% and 90.6% resp. 13 Key word Cnuclear agnetic resonance; FTIR spectru ; A ide; Si ple synthetic ethod , [9- 10] [ 11- 12] (Gln) DLL, [ 1] , ( ), , , [2] [3] [ 13] , , D [4- 6] (ena ides) , , L [7] 1, 8 , (), [8]