高流量氧雾化吸入与超声雾化吸入治疗COPDⅡ型呼吸衰竭的对比.pdfVIP

实用临床医学2007年第8卷第12期 PracticalClinical Medicine，2007，Vol 8，No12 高流量氧雾化吸入与超声雾化吸入 厶 JI=l疗COPDⅡ型呼吸衰竭的对比 张儒莲，历风元，潘俊华 (南昌市第一医院呼吸内科，南昌330008) 摘要：目的：探讨高流量氧雾化吸入治疗COPDII型呼吸衰竭的疗效。方法：8O例COPDII型呼吸衰竭患者分为试 验组(n一40，高流量氧雾化)与对照组(n一40，超声雾化)，分别吸入万托林雾化液。于治疗前 0．5 h和治疗后 0．5 h、24 h、3 d、4 d及治疗结束后行血气分析，并观察病情变化。结果：试验组PaOz明显提高，PaCOz降至正常。 试验组与对照组临床总有效率分别为97．5 、77．5％，不良反应率分别为7．5 、40 ，两组比较差异均有显著性 (P0．05)。结论：高流量氧雾化吸入可应用于COPDII型呼吸衰竭的治疗。 关键词：慢性阻塞性肺疾病；II型呼吸衰竭；高流量氧雾化；超声雾化 中图分类号：R563 文献标识码：A 文章编号：1009—8194(2007)12—0017一O3 The Effects of High Flow Oxygen Inhalator and Ultrasonic Inhalator on Patients withⅡRespiratory Failure due to Chronic Obstructive Pulmonary Disease ZHANG Ru。lian，LI Feng-yuan，PAN Jun。hua (Department of Respiratery Diseases，Nanchang First Hospital， Nanchang 330008，China) Abstract：Objective：To observe the effect of high flow oxygen inhalator for patients with II re— spiratory failure with chronic obstructive pulmonary disease．Methods：Eighty patients were di— vided into two groups：group A (high flow oxygen inhalator)and group B(ultrasonic inhalator)， all patients were used ventolin respirator solution at half an hour before the treated and half an hour，1，3，and 4 days after the treated．The arterial blood gas was measured and clinical syrup— toms were assessed before and after treated．Results：PaO2 was significantly increased，PaCO2 had a significant decrease in group A，PaO2 and PaCO2 had the significant differences in group B (PO．05)．The rate of effect were 97．5 and 77．5 in group A and B(PO．05)，respective— lY．The rate of the side effect were 7．5％ and 40 (PO．05)．Conclusion：The high flow oxygen inhalator is effective for patients with chronic obstructiv