无创正压通气治疗慢性阻塞性肺疾病引起的呼吸衰竭疗效分析.pdfVIP

． 338． 现代中西医结合杂志Modern Journal of Integrated Traditional Chinese and Western Medicine 2008 Jan，17(3) 无创正压通气治疗慢性阻塞性肺疾病引起的呼吸衰竭 疗效分析 薛秀杰，张宗辉，赵荣娟 (浙江萧山医院，浙江杭州311200) [摘要] 目的 评价无创正压通气对慢性阻塞性肺疾病(COPD)引起的呼吸衰竭的治疗价 值。方法 选择符合无创通气指征的C0PD急性加重并呼吸衰竭患者，在相关基础治疗的基础 上，予无创正压通气(NIPPV)，分析其最终预后与入院时测定指标的相关性。结果 无创通气 治疗成功率88．5％；无创通气成功者COPD出现呼吸衰竭至开始呼吸机治疗的时间、呼吸频率、 体质量指数、APACHElI评分、患者基础肺功能等与未成功者比较有显著性差异。结论 NIP— Pv治疗COPD并呼吸衰竭疗效确切、安全，可以减少有创通气的使用；适应证可适当放宽。 [关键词] 慢性阻塞性肺疾病；无创正压通气；呼吸衰竭 [中图分类号] R563．8 [文献标识码] A [文章编号] 1008～8849(2008)03—0338 03 Analysis of the effect of noninvasive positive pressure ventilation on treatment of respiratory failure of chronic obstructive pulmonary disease Xue Xiujie，Zhang Zonghui，Zhao Rongjuan (Xiaoshan Hospital of Zhejiang，Hangzhou 311200，Zhejiang，China) Abstract：0bjective It is tO assess the therapeutic effects of noninvasive positive pressure ventilation(NIPPV)on pa— tients with rcspiratory failure caused by chronic obstructive pulmonary disease(COPD)．Methods Patients in acute exacerba— tion stage of COPD who developing respiratory failure and who have the indication for NIPPV were selected in this study． The relationship between the prognosis and the indexes observed during hospitalization was analyzed on the basis of the ac— cording fundamental therapy combined with NIPPV．Results The Success rate with NIPPV was 88．5％：the ventilation time，respiratory frequency，AP ACHE lI score，and the basic lung function were significantly different in NIPPV group compared with the invasive mechanical ventilation group．Conclusion NIPPV is sa