非那雄胺治疗BPH伴发血尿-1陈方敏.pptVIP

非那雄胺治疗BPH合并血尿The study about Finasteride therapy of BPH complication with hematuria贵阳医学院附属医院 陈方敏 ? I级(轻度发作) ? 单次或多次发作，24小时内自行消退 经长期随访证实疗效良好 多数患者症状改善，不再发生血尿 推荐Finasteride作为BPH伴发血尿的一线疗法 FOLEY等UK研究 停药后血尿复发 术前用药减少TURP术中出血 Richard Harkaway et al. AUA 99’ 结论 前列腺体积大于30克患者在TURP术前用非那雄胺5毫克，可有效减少围手术期出血。 前列腺的腺泡及基质增生导致血管增生，这些增生的血管容易破裂，形成反复出血。 Bailey最近报道：伴有血尿的患者其前列腺的血管密度明显增高，在用非那雄胺后血管密度显著降低 止血作用4周内即可出现，因此可能并非仅是通过缩小前列腺体积。 这一发现对BPH伴发血尿具有重大影响。非那雄胺显著减少出血，表明BPH伴发血尿不再是一个手术指征。 即使需要手术，非那雄胺可减少术中出血，因为非那雄胺可导致前列腺缩小，血管减少。 目前建议 排除其他原因的肉眼血尿：结石/肿瘤等 影象学检查、细胞学检查、膀胱镜检查 确定分级/出血严重程度 药物治疗：非那雄胺 5mg/日 谢 谢 大 家 ！ 57例因BPH造成血尿的患者随机分组，28例接受保列治治疗，27例作为对照，随访一年。对照组中17例血尿复发，7例因此需要手术治疗；保列治组中4例复发血尿，无一例因此需要手术治疗。 * * 照片 Name Fangmin, Chen Gender Male Date of Birth Nov.5th,1970 Mailing Address Gui Wu Southern Road No.133, Guiang City,Guizhou Province, P.R.China ,550004 Mobile 08613984319766 Fax Email cfm_cn@ Work Experience From 1993 -2000, as a surgeon, I worked at Hanyang Railway Central Hospital in Wuhan. Since July 2005, as a Urologic surgeon, I have been working at Urologic department of Affiliated hospital to Guiyang Medical College. Education Background 1 2000.9-2005.6 Master-Doctor Degree Courses. Tongji Medical College of Huazhong Science Technology University, Hubei Province. 2009.2-2009.10, as a Fellow, studying abroad to Brady Urologic Center of Presbyterian hospital, Weill Cornell Medical College(WCMC), ranking 6th in U.S.A, NYC. my mentor in WCNC is Dr. Tewari, most prestigious Professor in U.S.A Skills Specialties As an AUA Member, I regularly receive special Journals (JU) and traning information from AUA. As a medical professor and mentor of Master Degree, I preside over 8 reseach projects including of NSFC, etc, which almost is majored in urologic oncology (e.g. prostate cancer). As an archiater, I have a specialty in mini-invasive therapies in Urology,such as Larparoscopy, TURP,Ureteroscopy and PCNL et