代谢综合症【心内科】.ppt

背景1 1988年Reaven首先注意到血脂异常、高血压、肥胖常聚集表现 1997年Zimmet提出代谢综合征的概念 1999年WHO正式进行工作定义 2004年中华医学会糖尿病学会提出了中国人的工作定义 2005年IDF颁布第一个全球统一定义 胰岛素抵抗的检测 高胰岛素钳夹试验 间歇采样静脉葡萄糖耐量试验 HOMA- IR测定 口服葡萄糖耐量试验 * * * A meta-analysis of 12 hypertension trials that included the development of heart failure demonstrated significant treatment benefits (1). The incidence of heart failure was reduced by 52% (CI 41-62%) compared to the control or placebo subjects. It is clear that the benefits in reducing heart failure in placebo-controlled trials are comparable, if not superior, to the reductions in stroke and coronary heart diseas