liposome—a novel drug delivery system 脂质体—神奇的药物递送 .pdf

Hans Journal of Medicinal Chemistry 药物化学, 2016, 4(3), 19-24 Published Online August 2016 in Hans. /journal/hjmce /10.12677/hjmce.2016.43003 Liposome—A Novel Drug Delivery System 1 2 3 Jibo Wang , Jimin Liu , Hongmei Yuan 1 School of Pharmacy, Medical Department of Qingdao University, Qingdao Shandong 2 Division of Microbiology, Medical Department of Qingdao University, Qingdao Shandong 3 Pharmacy Department, Qingdao Municipal Hospital, Qingdao Shandong th th th Received: Oct. 27 , 2016; accepted: Nov. 12 , 2016; published: Nov. 15 , 2016 Copyright © 2016 by authors and Hans Publishers Inc. This work is licensed under the Creative Commons Attribution International License (CC BY). /licenses/by/4.0/ Open Access Abstract The study of liposome has become a focus in physical pharmacy recently and showed the prospec- tive value of application in many ways. The summarization of origin, basic concept, types, prepa- ration, in vivo characteristics, quality control and application of liposome was made. The stability and target design of liposome are the fundamentality of its application. The future development of liposome was viewed. Keywords Liposome, Drug Delivery System, Stability, Lipid Bilayer, Target 脂质体—神奇的药物递送系统 1 2 3 王继波 ，刘继民 ，袁红梅 1青岛大学医学部药学院，山东 青岛 2青岛大学医学部微生物教研室，山东 青岛 3青岛市立医院药剂科，山东 青岛 收稿日期：2016年10月27 日；录用日期：2016年11月12 日；发布日期：2016年11月15 日 摘 要 近年来，脂质体已成为物理药学领域研究的热点，并且已经在许多方面显示出其潜在的应用价值。本文 文章引用: 王继波, 刘继民, 袁红梅. 脂质体—神奇的药物递送系统[J]. 药物化学, 2016, 4(3): 19-24. /10.12677/hjmce.2016.43003 王继波 等 综述了脂质体的起源、基本概念、类型、制备方法、体内特性、质量