茜草提取物对大强度耐力训练大鼠不同组织no - 北京体育大学学报.doc

紫草提取物对耐力训练大鼠力竭和恢复24h后 肝组织及线粒体保护作用的实验研究 徐小仙1 ，熊正英2 ((1西安大学体育部 陕西 西安 7100陕西 西安 7100) 摘 要：目的：耐力训练大鼠。方法：只随机分组、，每组只。进行6周跑台训练，一次性力竭运动一次性力竭运动。结果：大鼠在力竭运动后，肝组织抗氧化能力显著下降(P0.05)，NOS合酶活性和NO含量显著降低(P0.01)，线粒体Na+,K+-ATPase、Ca2+,Mg2+-ATPase酶的活性显著降低(P0.05)，24h后，各指标恢复不明显。补充紫草组大鼠在力竭运动后，与力竭组大鼠相比，肝组织抗氧化能力、NOS合酶活性和NO含量、线粒体Na+,K+-ATPase、Ca2+,Mg2+-ATPase酶的活性都显著升高(P0.05)；24h后，各指标基本恢复到基础水平。结论：外源性补充紫草提取物可以有效，延缓运动疲劳的产生，促进运动后机体功能恢复关键词提取物；中图分类号：G804.7 文献标识码：A Effect of Gromwell Extract on the protection with hepatic tissue and mitochondria in exhaustive and 24h-resting endurance-trained Rats XU Xiao-Xian，XIONG Zheng-Ying (1Physical education Department, Xian Shiyou University，Xi an 710065，Shaanxi) (2Institute of Sports Biology,Shaanxi Normal University，Xi an 710062，Shaanxi) Abstract: Purpose: Through the observation of biochemical indicator with hepatic tissue and mitochondria in once exhausting and 24 hour resting with endurance-trained Rats, discussing the biological mechanism of Gromwell extract impacting to protect liver, improve sports abilities, delay sports fatigue and recovery. Method: Choose 40 rats, and divide them into 5 groups--Exercise group(group A), exhausted exercise group(group B), exhausted exercise and 24h recovery group(group C), gromwell with exhausted exercise group(group D), gromwell with exhausted exercise and 24h recovery group (group E). Five group all have been trained 6 weeks. At last time, group A was not trained as usually and adopted samples immediately, group B and D were trained by exhausted exercise and then adopted samples, group C and E were trained by exhausted exercise and had 24h recovery then adopted samples. Result: After the exhaustive exercise, the anti-oxidation ability of hepatic tissue can lower greatly(P0.05), the activities of NOS and the contents of NO with hepatic tissue can lower greatly (P0.01), the activities of Na+,K+-ATPase and Ca2+,Mg2+-ATPase with hepatic mitochondria can lower greatly (P0.05), after 24 hours, these indi