食管癌术后脑转移17例临床分析.pdfVIP

· 372· 塞旦蕉垂垒查 生!旦筮垫卷筮4期 The Practical Journal ofcancer ． Ju【v 2008．V0l 23．N0．4 食管癌术后脑转移17例临床分析 翁向群 庄聪文 程先进 陈 苏 杨胜生 曾志勇 张哲明 张荣良 【摘要】 目的 探讨食管癌术后脑转移的临床特点及治疗方法。方法 对1993年4月 2005年6月收治的17例 食管癌术后脑转移患者的临床特点和治疗方法进行回顾性分析。结果 全组平均生存时间为26．3个月，7例单纯脑转 移切除平均生存时间为17．7个月，3例手术切除联合放疗平均生存时间为65．5个月。结论 食管癌术后脑转移预后不 良，治疗原则上应采用以手术切除联合放疗为主的综合治疗。 【关键词】食管癌术后；脑转移；全脑照射；预后 中图分类号：R735．1 文献标识码：A 文章编号：1001—5930(2008)04-0372-02 Clinical Analysis of 1 7 Patients with Brain Metastasis from Esophageal Carcinoma after Surgical Treatment WENG Xiang-qun，ZHUANG Cong-wen，CHEN Xian-fin，et a1． Fuzhou General Hospital of Na ng Military District，Fuzhou， 350025 【Abstract】Objective To analyze the clinical features and treatment methods of esophageal carcinoma with brain metas． tasis after surgical treatment．Methods Data of 17 cases with brain metastasis after surgical treatment of esophageal carcinoma were analyzed retrospectively．Results The median survival after the diagnosis of brain metastasis Was 26．2 months．7 patients Were treated by resection alone，and the median survival Was 1 7．7 months．3 patients were treated by resection of the tumor com- bined with radiotherapy，and the median survival Was 65．5 months．Conclusion Th e prognosis of patients with brain metastasis after surgical treatment of esophageal carcinoma was poor．Resection of the tumor followed by WBRT seemed to be the indicated treatment for these patients． 【Key words】Postoperation of esophageal carcinoma；Brain metastasis；Whole brain radiation(WBRT)；Prognosis (The Practical Journal ofCancer，2008，23：372—373) 脑转移瘤的原发肿瘤最常见为肺癌、乳腺癌和黑 小脑5例，大脑4例，脑干1例，多发部位7例。从食 色素瘤，而食管癌转移至脑部临床上较为少见，文献报 管癌术后到发现脑转移的平均