中药保留灌肠治疗湿热瘀结型慢性盆腔炎的临床探究.pdfVIP

提 要 目的：探讨中药保留灌肠治疗湿热瘀结型慢性盆腔炎的临床疗效及其作用机理， 旨在寻找一个安全、方便、有效的外用治疗方法。 方法：将60例慢性盆腔炎患者随机分成两组：治疗组30例（予盆腔炎灌肠方保 留灌肠）；对照组30例（予康妇消炎栓直肠给药）。观察两组患者治疗前后中医证候、 局部体征的改善情况；治疗前后两组患者血液流变学、血清白细胞介素-2（IL-2）、 肿瘤坏死因子（TNF- ）、子宫动脉血流、盆腔B超变化的情况。 结果：治疗组综合疗效总有效率为 93.3%，对照组为 66.7%，差异有统计学意义 （P0.01）。治疗组中医证候疗效总有效率为93.3%，对照组总有效率为70.0%，差异 有统计学意义(P0.01)。两组患者治疗后中医证候积分、局部体征积分较治疗前均明 显降低，并且治疗组优于对照组，差异有显著性(P0.01)。治疗组在改善血流变指标、 子宫动脉血流状况、升高 IL-2、降低 TNF- 、缩小盆腔炎性包块、减少盆腔积液等 方面均优于对照组（P0.05）。治疗过程中未发现明显不良反应。 结论：盆腔炎灌肠方治疗湿热瘀结型慢性盆腔炎的临床疗效较好，其机理可能是 通过改善患者体内血液高凝状态及子宫动脉血流、调节机体的免疫功能，使患者的临 床症状和体征得到改善，值得进一步研究和临床推广。 关键词 慢性盆腔炎；湿热瘀结；中药保留灌肠 Clinical Effect Observation Of Chinese Herbal Medicine Retention Enema Therapy To Treat Chronic Pelvic Inflammatory Disease Of Hot And Samp Stasis Specialty：Gynecology of TCM Tutor：Lv Mei Author ：Zhang Hui Abstract Objective:To observe the clinical effect of Chinese Herbal Medicine retention enema to treat chronic pelvic inflammatory disease of humid heat stagnation ,hence be a scientific and credible evaluation, aimed at finding a safe 、convenient and efficient with topical treatments. Methods: 60 case of CPID patients were randomly divided into two group :treatment group(30 cases,treated with PenQiangYanGuanChang Fang for Chinese Herbal Medicine retention enema ) and control group (30 cases ,treated with KangFuXiaoYan suppository by rectal administration).The improvement of traditional chinese medicine syndrome ,local physical sign and the changes in the hemorheology ,the level of IL-2、TNF-,the change of the uterine blood circulation 、the pelvic B ultrasound were observed and compared. Results:The total effective rate was 93.3% in the treated group,while it was 66.7% in the control group,the difference was statis