固本舒脉汤治疗老年难治性心绞痛阳虚脉阻型的临床探究.pdfVIP

提 要 目的：观察固本舒脉汤治疗老年难治性心绞痛的临床疗效并探讨其作用机制。 方法：临床研究将 60 例老年难治性心绞痛阳虚脉阻型患者随机分为两组，治疗 组30例，给予固本舒脉汤结合西医常规治疗；对照组30例，给予西医常规治疗，疗 程60天。 结果：1、固本舒脉汤治疗老年难治性心绞痛疾病疗效总有效率 83.4%，显效率 56.6%；2、心绞痛疗效治疗组总有效率86.7%，显效率60%；3、动态心电图疗效总有 效率 73.4%，显效率 43.3%；4、中医症状改善总有效率 90%，显效率 46.7%，均明显 优于对照组（P＜0.05 或 P＜0.01）；5、治疗组治疗前后比较，治疗组与对照组，固 本舒脉汤结合西医常规治疗可显著降低 TG、LDL-C、TC、提高 HDL-C，与对照组相比 有显著差异（P＜0.05或P＜0.01）。 结论：本研究完善了中药在现代危重病治疗的理论内容，肯定了中医药在危重病 治疗中的作用，认为固本舒脉汤结合西医常规治疗在改善老年难治性心绞痛的病情方 面疗效显著，为进一步深入研究中药治疗难治性疾病奠定了基础。 关键词 固本舒脉汤；老年难治性心绞痛；阳虚脉阻；临床研究 The Clinical Study on anginapectoris of elder patients with Refractory Angina by Gubenshumai Formula Speciality：Internal Medicine of Traditional Chinese Medicine Author ：Fang Lihua Tutor ：Prof.Bao Pei-rong Abstract Objective: The clinical efficacy of the observed strengthening the foundation Shu decoction treatment of elderly patients with refractory angina pectoris and to explore its mechanism Methods: The clinical study of 60 cases of elderly refractory angina pectoris yang pulse resistance were randomly divided into two groups , treatment group 30 cases , the combination of conventional Western medicine treatment given to strengthening the economy Shumai Soup ; control group ( n = 30 ) , giving Western conventional treatment course of 60 days . Results: 1 Guben Shumai Soup disease efficacy of the treatment of elderly refractory angina total efficiency of 83.4% , markedly effective rate 56.6% ; angina treatment group the total effective rate was 86.7 , markedly effective rate was 60% ; ECG efficacy , efficiency 73.4% , markedly effective rate 43.3% ; , clinical symptoms to improve the total efficiency of 90% , markedly effective rate was 46.7% , signi