影响肺癌术后复发转移的因素(Factors influencing the recurrence of lung cancer after surgery).docVIP

影响肺癌术后复发转移的因素(Factors influencing the recurrence of lung cancer after surgery).doc

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影响肺癌术后复发转移的因素(Factors influencing the recurrence of lung cancer after surgery)

影响肺癌术后复发转移的因素(Factors influencing the recurrence of lung cancer after surgery) Factors influencing the recurrence of lung cancer after surgery Postoperative recurrence of lung cancer is one of the important factors affecting the survival of lung cancer patients. According to statistics, even in patients with stage I non-small cell lung cancer, radical surgical resection is performed, and there are still more than 30% of patients who cannot be cured or died. This is largely due to postoperative recurrence and metastasis. Therefore, it is of great significance to understand the pathologic mechanism of recurrence after lung cancer. The following are some of the factors that experts summarize in the postoperative metastasis of non-small cell lung cancer. 1. Reasons for the recurrence of NSCLC Has now confirmed that cancer cells formed from the initial mutation to less than 3 mm, existing form and.cause the capillaries, due to the capillary basement membrane of discontinuity, the cancer cells are easily enter blood circulation for an opportunity to spread all over my body. In the course of development, tumor cells can be disseminated and survive in blood circulation, lymphatic channel, bone marrow, and organs of tissues, forming micrometastases. Micro metastases in the body has not formed nodules, and without any clinical symptoms, routine inspection methods such as imaging, clinical pathology method is difficult to test found that at this point, although by improving operation method is relatively complete resection of the primary tumor and lymph node cleaning, but invisible micrometastases lesions actually exists. The presence of micrometastases is the basis of the metastasis of NSCLC. The surgical treatment itself is one of the reasons to promote the recurrence of NSCLC. On the one hand, surgical operation can cause tumor cells to spread into the blood circulation, leading to the recurrence of tumor postoperative metastasis; On the other hand, the selection of surgica

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