琼胶低聚糖清除自由基的活性 - 水产学报.pdfVIP

27 3 Vol. 27, No. 3 2003 6 JOURNAL OF FISHERIES OF CHINA Ju e, 2003 : 1000- 0615( 2003) 03- 0283- 06 薛长湖, 徐 强, 赵 雪, 李兆杰, 林 洪 ( , 266003) : DPPH , ML #OH O #- , IC 0. 05 mg#mL- 10.7 mg#mL- 1, 2 50 ML DPPH ( IC 6. 4mg#mL - 1) , 50 Vc O2#- , ML LPS+ D- GalN , ML GPT MDA , SOD GSH-Px , : ; ; ; : S948 :A Radical scavenging ability of agar oligomers XUE Cha g-hu, XU Qia g, ZHAO Xue, LI Zhao-jie, LIN Ho g ( Dep artment of Food S cience and Technology , Ocean University of Qingdao , Qingdao 266003, China) Abstract: The free oxyge radical scave gi g effects of agar oligomers were studied by the method for determi atio of Lumi esece ce a d DPPH assay. The results showed that agar oligomer ML had stro g #- - 1 - 1 scave gi g effects o #OH a d O , IC were 0. 05mg#mL a d 0. 7mg#mL , but the scave gi g effect o 2 50 #- DPPH radical was much lower tha Vc a d probutol. Comparatio of the scave gi g activities o O2 betwee agar Oligomers with differe t sulphate co te t a d molecular weight showed that high sulphate group or high molecular weight took the mai actio to scave ge radicals. Agar oligomers take ig to LPS+ D- GalN i duced liver i jury mice could effectively i hibit the i rease of GPT acticity a d MDA co te t, a d mai tai the acitivities of SODGSH- Px activity i mice serum. It had good protective effect o liver i jury. Key words: aga