活血消癥方治疗子宫腺肌病的临床探究.pdfVIP

提 要 目的：观察活血消癥方治疗子宫腺肌病的临床疗效并探讨其作用机理。方法：共 观察子宫腺肌病患者 60 例，将其按照随机数字表法分组，其中治疗组 30 例，予活血 消癥方治疗，对照组 30 例，予丹莪妇康煎膏口服。观察两组痛经疗效、血清雌二醇 （E ）、血栓烷素B （TXB ）、一氧化氮（NO ）及子宫体积的变化。结果：治疗后两 2 2 2 组患者痛经疗效比较，治疗组为 76.67%，对照组为 63.33%，两组比较有显著性差异 （P0.05 ），治疗组优于对照组。治疗后两组患者中医症状总积分组间比较有非常显 著性差异（P0.01 ）；两组患者治疗后血清E2 、TXB2 及 NO 含量较治疗前明显降低， 与治疗前相比均有非常显著性差异（P0.01 ），疗后组间比较除 TXB2 外均有显著性 差异（P0.05 或 P0.01 ）；治疗后两组患者子宫体积较治疗前明显缩小，与治疗前相 比有非常显著性差异（P0.01 ），与对照组比较有显著性差异（P0.05 ）。结论：中药 活血消癥方治疗子宫腺肌病疗效较好，其机理可能与改善患者体内血液高凝及血管收 缩状态，减少病变部位致痛物质及炎性介质的含量等多个作用环节有关。 关键词 子宫腺肌病； 活血消癥方；临床研究 The Clinical Research on the Effect of HuoXueXiaoZheng Fang in Treating Adenomyosis Speciality: Gynecology of TCM, The study of menstruation sickness and sterility Tutor: Professor Ye Qing Author: Zhang Zong Ying Abstract Objective: Observe the clinical curative effect of HuoXueXiaoZheng Fang, which is applied to treat adenomyosis, and explore it work mechanism. Methods: We totally observed 60 patients of adenomyosis and it was divided into two groups randomly. The treatment group take HuoXueXiaoZheng Fang, while the control group take DanEFuKang paste, which are compared to observe their curative effects and impacts on Serum estradiol (E ) 、Thromboxane (TXB ) 、Nitric oxide (NO) and Uterine volume. Results: After 2 2 treatment, the dysmenorrhea effect of the treatment group was 76.67% ,while the dysmenorrhea effect of the control group was 63.33% and there were significant differences between groups (P0.05). The syndrome score of t