活血消癥胶囊及化瘀止痛胶囊分期治疗子宫腺肌病痛经的临床研究.pdfVIP

提 要 目的：观察活血消癥胶囊和化瘀止痛胶囊分期治疗血瘀气滞、痰郁互结型子宫腺 肌病痛经的临床疗效并探讨其作用机理。方法：共观察子宫腺肌病患者 60 例，治疗 组30例，分期服用活血消癥胶囊和化瘀止痛胶囊；对照组30例，分期服用桂枝茯苓 胶囊和元胡止痛软胶囊，观察两组患者痛经疗效及对血液流变学、血管内皮素-1、前 列腺素 E 的影响。结果：两组患者治疗后痛经症状明显改善，组间比较疗效有显著 2 性差异（P0.05）；两组血液流变学相关指标改善明显，均较疗前有显著性差异 （P0.05），组间比较有显著性差异（P0.05）；两组患者疗后血管内皮素－1均降低， 较疗前有显著性差异（P0.05），组间比较有显著性差异（P0.05）。两组患者疗后血 清前列腺素 E 均降低，较疗前有显著性差异（P0.01），组间比较有显著性差异 2 （ P0.01）。结论：活血消癥胶囊和化瘀止痛胶囊分期治疗子宫腺肌病痛经疗效较好， 其机理可能与改善体内血液高凝状态，改善血管内皮功能，减少炎性增生渗出等有关。 关键词 分期治疗；子宫腺肌病；痛经；临床研究 the Clinical Research on the Effect of HuoXueXiaoZheng Capsule and HuaYuZhiTong Capsule in Treating Adenomyosis Dysmenorrhea by stages Speciality: Gynecology of TCM,The study of menstruation sickness and sterility Tutor: Professor Ye Qing Author: ZhangFuHua Abstract Objective: To observe the clinical curative effect of treating Adenomyosis Dysmenorrhea by stages using HuoXueXiaoZheng(HXXZ) capsule and HuaYuZhiTong （HYZT ） capsule and explore its effect mechanism. Methods: 60 patients of Adenomyosis Dysmenorrhea were divided in two groups randomly,30 cases of the treatment group using HXXZ capsule and HYZT capsule by stages , 30 cases of the control group using GZFL capsule and HYZT capsule by stages .To observe the effect of the treatment of two groups and the impact on blood rheology 、vascular endothelin-1 、 prostaglandin E . Results: The dysmenorrhea symptoms of the two groups were obviously 2 improved(P0.05) after treatment and there were significant differences between groups (P0.05). After the treatment,both the blood rheology indica