清肝利湿汤联合二甲双胍治疗多囊卵巢综合征肝经湿热证的临床探究.pdfVIP

提 要 目的：观察清肝利湿汤联合二甲双胍治疗多囊卵巢综合征肝经湿热证的临床疗 效，并初步探讨其作用机理。方法：将49例多囊卵巢综合征患者随机分为两组，治 疗组25例，口服清肝利湿汤及二甲双胍；对照组 24例，口服二甲双胍，观察治疗前 后临床表现和中医证候改善情况及生殖内分泌激素、空腹血糖、空腹胰岛素等的变化。 结果：治疗组治疗多囊卵巢综合征的总有效率为96.00%，对照组总有效率为87.50%， 两组比较差异有显著性（P0.05）；治疗组对症状的改善明显优于对照组，差异有显 著性（P0.05）；治疗组对空腹胰岛素、黄体生成激素的改善均明显优于对照组，差 异有显著性（P0.05）；经随访观察治疗组在诱导排卵和改善月经方面稳定性优于对 照组，差异有显著性（P0.05）。结论：清肝利湿汤联合二甲双胍能有效改善临床症 状，明显降低空腹胰岛素水平。 关键词 多囊卵巢综合征； 肝经湿热证； 清肝利湿汤； 临床研究 Clinical Research on the Effect of QingGanLiShi Decoction Treating the Polycystic Ovary Syndrome(PCOS) in the Muggy Syndrome OF Liver Channels Speciality:Gynecology of TCM Tutor:Pro.Lv Mei Author:Ji Xiuzhen Abstract Objective: To observe the clinical effect and mechanism of QingGan LiShi Decoction(QGLS) with Metformin treating the Polycystic Ovary Syndrome(PCOS) in the muggy syndrome of liver Channels. Methods:Forty-nine women with PCOS were divided randomly into two groups: test group (25 cases, treated with QGLS and Metformin ) and control group(24 cases,treated only with Metformin).The changes of clinical symptoms and signs, reproduced internal secretion hormones( FSH 、LH 、T) levels, limosis blood sugar levels, and limosis insulin levels (FINS) were observed. Results:The total effective rate of the test group was 96.00%,while that of the control group was 87.50% .The statistic difference between them was significant (P0.05). QGLS is effective on improving the clinical symptoms and physical signs.After the following-up observation, the inducing ovulation and the stability of making emmenia sides better were significant and the test group was superior to the control one (P0.05).Conclusion: QGLS with Metformin can imp