益肾止渴合剂治疗早期糖尿病肾病的临床探究.pdfVIP

提 要 目的：观察益肾止渴合剂治疗早期糖尿病肾病，证属脾肾两虚、痰浊血瘀型的临 床疗效，并从现代医学角度深入探索其作用机理，探索中西医结合治疗该病的新方法。 方法：将临床诊断为早期糖尿病肾病属脾肾两虚、痰浊血瘀型的200例患者随机分为 两组，治疗组100例，予以益肾止渴合剂配合贝那普利治疗；对照组100例，予以贝 那普利治疗，用药4周为一个疗程，连续两个疗程。结果：临床观察发现，益肾止渴 合剂治疗组在改善本病症状和体征方面明显优于对照组（P0.05）；在改善尿蛋白方 面优于对照组（P0.05）；在改善血脂方面明显优于对照组（P0.05）。并且在治疗过 程中未发生不良反应，临床用药安全。结论：临床观察表明益肾止渴合剂治疗早期糖 尿病肾病疗效可靠，不良反应小，值得进一步研究。 关键词 益肾止渴合剂；早期糖尿病肾病；临床研究 Clinical Observation of Early Stage Diabetic Nephropathy in treatment with Tonifying Kidney-Thirst Mixture Speciality: Combined Chinese and modern medical Author: Gengfeng Tuthor: Professor fengjianhua Abstract Objective: To observe the clinical results of Tonifying Kidney-Thirst Mixture in curing early stage diabetic nephropathy,which was asthenia of both the spleen and kidney type, phlegm stagnancy and blood stasis type.To investigate the mechanism of this from the modern medicine angles,and to probe a new therapeutic method in curing this disease by conbined treatment of traditional Chinese medicine and western medicine. Method: 200 patients diagnosed early stage diabetic nephropathy were divided into two groups stochasticly, 100 patients who taken Tonifying Kidney-Thirst Mixture and Benazepril as treatment group,other 100 patients as control group given Benazepril only.4 weeks as a course of the treatment,and need two continuous course. Result: The symptoms and signs, Urine protein,and blood fat of the treatment group had been significantly improved contrasting with the control group after treatment （P0.05 ）.There was no untoward effect in the course of the treatment.It was safe in the clinical medication. Conclusion: It was eutherapeutic in curing the early stage diabetic nephropathy by Tonifying Kidney-Thirst Mixture