益肾调更汤治疗肾阴阳两虚型围绝经期综合征的临床探究.pdfVIP

提 要 目的：观察益肾调更汤治疗肾阴阳两虚型围绝经期综合征的临床疗效，并探讨其 作用机制。方法：选择 60 例围绝经期综合征患者，观察分析治疗前后临床症状的改 善情况，并分别测定雌二醇（E ）、促卵泡生成激素（FSH）、促黄体生成激素（LH）、 2 β-内啡肽（β-EP）、甲状旁腺激素（PTH）、降钙素（CT）、白介素-2（IL-2）比较其 治疗前后的变化情况，临床研究用自身前后对照的研究方法，观察 60 例围绝经期综 合征患者。结果：治疗后与治疗前相比患者临床症状明显改善，临床总有效率98.33%， Kupperman 评分有非常显著性差异（P0.01），治疗后患者血清 FSH、LH 水平较治疗 前下降，E2 水平较治疗前升高，差异有显著性（P0.05）；β-EP、CT、IL-2 水平较 治疗前升高（P0.05）；PTH水平较治疗前降低（P0.05）；结论：益肾调更汤对围绝 经期综合征有较好的治疗作用，能有效缓解时而烘热汗出、时而畏寒、腰膝酸痛、失 眠多梦等围绝经期症状，其作用是通过从整体上纠正紊乱的内分泌及植物神经紊乱， 改善失调的骨代谢，是治疗围绝经期综合征的有效方药。 关键词 围绝经期综合征；肾阴阳两虚；益肾调更汤；中医药疗法 The Clinical Study of Treating Peripheral Menopause Syndrome (PMS) With The Decoction of Yi-shen-tiao-geng Speciality：Gynecology of TCM Tutor：Pro. Wu Xinhua Author ：Liu Di Abstract Objective: To study the therapeutical effect of the decoction of Yi-shen-tiao-geng on peripheral menopause syndrome(PMS), and to explore its action mechanism. Methods: We selected 60 patients with PMS, observe the clinical symptoms improvement after treatment and detect the concentration of E2 、FSH 、LH 、β-EP、PTH 、CT、 IL-2 in the blood. Results:The clinical symptoms are significantly improved and the clinical total efficiency is 98.33%.The improvement of Kupperman scores is very significant (P0.01). After treatment, the concentration of FSH, LH in the blood is lowered, while the concentration of E2 in the blood is raised (P0.05). The concentration of β-EP、CT、IL-2 is significantly evaluated after treatment,while the PTH are remarkably reduced(P0.05). Conclusions: Yi-shen-tiao-geng on peri-menopausal period of liver syndrome has good therapeutic effect, Can effectively relieve sometimes hot flashes sweated, sometimes chills, waist knees ache, insomnia and have many dreams wai