益气活血通脉合剂治疗2型糖尿病周围神经病变的临床探究.pdfVIP

提 要 目的：观察益气活血通脉合剂对2型糖尿病周围神经病变的疗效。探讨益气活血 通脉合剂治疗2型糖尿病周围神经病变的机制，并为临床治疗提供理论及应用价值。 方法：入选符合试验标准的2型糖尿病周围神经病变患者60例，并随机分为2组，其中 治疗组30例，对照组30例，均要求在血糖控制良好的基础上，治疗组给予益气活血通 脉合剂治疗；对照组给予糖脉康颗粒治疗。疗效观察时间为8周（共一个疗程）。观察 患者治疗前后的临床症状，以及空腹血糖、餐后血糖、血脂、血流变、神经传导速度 等指标。结果：经临床观察，治疗组在本病的临床症状改善方面，以及血糖、血脂等 的指标改善优于对照组（P0.05）；神经传导速度、血流变等方面的疗效明显优于对 照组（P0.01）；在治疗过程中尚未发生不良反应。结论：临床观察表明益气活血通 脉合剂治疗2型糖尿病周围神经病变，可明显改善患者的临床症状，以及患者的血糖、 血脂、神经传导速度、血流变等指标，在纠正患者血液的高凝状态，改善神经传导速 度以及预防周围神经病变方面疗效显著，并且无明显不良反应，是预防和治疗糖尿病 周围神经病变的有效方法，值得进一步研究和推广。 关键词 2型糖尿病；周围神经病变；益气活血通脉合剂 Clinical Study on Treatment of Peripheral Neuropathy Disease Caused by Type 2 Diabetes With Yiqihuoxuetongmai pulse Mixture Speciality: Internal Medicine of TCM Author: Zhang guifen Tutor: Professor Zhao quanlin Abstract Object: To investigate the effects of Yiqi huoxue tongmai pulse Mixture on peripheral neuropathy disease in type 2 diabetic patients related factors. To investigate Yiqi huoxue tongmai pulse mixture of peripheral neuropathy in the treatment of diabetes, and the mechanism of clinical theory value and provide application value. Methods: In accord with test standards of peripheral neuropathy in diabetes patients 60 cases, and randomly divided into two groups, including 30 cases in treatment group and control group in 30 cases, Under the basic premise of reducing the blood plasma glucose, 30 patients were treated with Yiqi huoxue tongmai pulse mixture in treated group ,others were treated with Tangmaikang Keli in control group. Clinical observation on time for eight weeks (a period of treatment). Observe patients before and after treatment of the clinical symptoms, and fasting and postprandial