益气养阴清肝方治疗阴虚阳亢型Graves病的临床疗效视察.pdfVIP

提 要 目的:观察益气养阴清肝方在治疗中医辨证属于阴虚阳亢型 Graves 病的临床疗 效，比较中药与西药在消除甲状腺肿大疗效上的差异，以及对患者实验室相关指标的 影响，为临床使用提供理论依据。 方法:采用随机、对照的方法,将60例阴虚阳亢型Graves病患者随机分为治疗组 和对照组，各 30 例。所有受试者在接受治疗时均进行基础治疗，治疗组在此基础上 加用中药益气养阴清肝方进行治疗，对照组在此基础上加用他巴唑进行治疗。观察时 间为8周，主要观察指标：临床症状、心率、体重、基础代谢率、甲状腺肿、突眼度、 甲功、肝功、血常规等。 结果：治疗组治疗后临床症状积分、心率、体重、基础代谢率、甲状腺肿、突眼 度、甲功等较前改善明显，与对照组比较有显著性差异。试验期间未发现不良反应。 结论：益气养阴清肝方联合行为干预方式对阴虚阳亢型Graves病患者疗效显著， 可以明显改善患者临床症状、心率、体重、基础代谢率、甲状腺肿、突眼度、甲功等， 且用药安全，证明了中医药辩证论治的有效性，正确运用中医药辨证施治治疗Graves 病前景广阔。 关键词 临床观察；Graves 病；阴虚阳亢型；益气养阴清肝方 The Clinical Observation in Treating Qi and Yin deficiency syndrome of Graves Disease with YiQiYangYinQingGanFang Specialty：Internal Medicine of Traditional Chinese Medicine Author ：Sun Xumin Tutor：Pro.Xu Yunsheng Abstract Objective ：Observe the clinical curative effection of Chinese patent drug“Yi QiYangYinQing GanFang” in treating Qi and Yin deficiency syndrome of Graves Disease,the difference effect between Chinese medicine and western medicine in removing Thyromegaly is compared，and there effects in some laboratory data are also compared， Offering a theoretical basis for the clinical use. Methods ：Taking the method of random and antitheses，60 patients with Qi and Yin deficiency syndrome of Graves Disease were divided into treatment group （n=30 ） and the control group（n=30 ）. All the participants had received the basic cure， the treatment group received the basic cure plus YiQiYangYinQingGanFang ，another group received the basic cure plus tapazole.Observation time last for 8weeks，the main outcome measures are as follows ：the clinical symptoms ，heart rate ，weight ，basal metabolic rate （BMR ），thyrocele ， protruding eyes degrees ，thyroid function ，liver function，blood routine examination and so on. R