益气养阴解毒法联合化疗治疗中晚期非小细胞肺癌的临床探究.pdfVIP

提 要 目的：针对中晚期非小细胞肺癌（NSCLC）患者“毒、虚”之病机特点，观察益 气养阴解毒法治疗中晚期非小细胞肺癌的临床疗效及其对毒副反应、免疫功能的影 响，并探讨其作用机理。方法：将 40 例中晚期非小细胞肺癌患者，随机分为两组。 治疗组 20 例，采用益气养阴解毒法联合化疗；对照组 20 例，单纯采用化疗。28 天 为1个周期。连续治疗4个周期后观察两组疗效，进行评价。结果：治疗组实体瘤疗 效、免疫功能提高、生活质量改善、临床症状缓解、肿瘤标记物下降等明显优于对照 组（P＜0.05），毒副反应明显低于对照组（P＜0.05），12月生存率高于对照组（P＜ 0.05）。结论：益气养阴解毒法能明显提高中晚期非小细胞肺癌患者化疗后免疫功能， 改善患者临床症状，提高患者生活质量，降低化疗药物毒副反应，是中西医结合治疗 非小细胞肺癌积极有效的方法。 关键词 非小细胞肺癌；益气养阴解毒法；化疗；免疫功能；中西医结合 Studies of Yiqi Yangyin Jiedu Therapy in Treatment with Non-small Cell Lung Cancer Specialty：Intergrated Traditional and Western Internal Medicine Author ：Wang Hongyan Tutor：Prof. Chen Zetao Abstract Objective ：To the pathogenesis characteristic of non-small cell lung cancer (NSCLC) patients ’ “toxic、deficiency”，to observe the effct and the influence of immunologic function of Yiqi Yangyin Jiedu therapy in treating patients with non-small cell lung cancer (NSCLC) and discusse the mechanism.Methods ：Adopting randomized method, the 40 patients enrolled were assigned to the treated group (20cases) and the control group (20cases). The control group was treated by chemotherapy alone, while the treated group treated by chemotherapy combined with Yiqi Yangyin Jiedu therapy. Twenty-eight days is one period.Observe and evaluate the therapeutic effect after four continual periods. Results:The entity lump volume 、immunologic function、tumor markers 、quality of life、 clinical symptoms improvement、toxic-side effects of the treated group are better than the control group （P ＜0.05 ），and there was difference in 12month survival rate （P ＜ 0.05 ）.Conclusion:Yiqi Yangyin Jiedu therapy can improve immunologic function after chemotherapy、improve quality